I've written lots of queries with about a 99 percent rejection rate. My few successes have been with independent publishers who have open submissions year-round or have a small window when they accept submissions. Authorspublish.com is an excellent website for information on when these windows open. Agents also operate this way, so your response time will be short if you know someone in the business, a teacher, or a fellow writer of novels or screenplays in the same genre as yours who can give you advice or names of people they know or have met. Several free and pay-to-play websites have gathered agents' request and their availability to new clients. Discovering the next great writer is essential to their continued success, so don't waste their time if they specialize in two or three genres and your work doesn't fit into any of those. Manuscript Wish List and Querytracker are great resources. Screenplay writers have similar websites available. Some are subscription serv...